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Gastroesophageal Reflux disease
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Gastro Esophageal reflux Disease (GERD)

What is GERD?--

It is a condition in which the gastric contents reflux back into the esophagus. Small amount of reflux is normal & is present in many people. However when it becomes excessive & begins to irritate the esophageal lining cells it is called GERD.

What causes GERD?--

GERD occurs when the lower esophageal sphincter fails to maintain a barrier between the stomach & the esophagus. This can be caused by various factors. One of the common reversible factor is obesity.

What are the symptoms--

  • Heartburn
  • Regurgitation of bitter fluid into the back of the mouth.
  • Sometimes, cough & voice disorder.

The symptoms are most likely after meals. They are often exacerbated by bending, lifting heavy weights.

What investigations are required for GERD?--

Generally GERD is a clinical diagnosis. Esophagogastroduodenoscopy may be required in some cases. Advanced investigations like esophageal pH monitoring & manometry are rarely required.

esophagoscopic view showing inflammed esophagus due to GERD
Esophagoscopic view showing inflammed esophagus due to GERD

Treatment--

Very important factor in treatment of GERD is the dietary & lifestyle changes.

  • Raise the head of the bed by 6 inches.
  • Have dinner early. Go to bed at least 2-3 hours after having dinner.
  • Smaller frequent meals are preferable to larger bulkier meals.
  • Lose weight if obese.
  • Avoid smoking.
  • Avoid peppermint, chocolate & alcohol; they reduce the tone of the lower esophageal sphincter.

Drugs--

  • Antacids & alginates--do provide symptomatic relief but not very useful for long term management.
  • Prokinetics--Cisapride increases the tone of the sphincter.
  • H2 receptor blockers--eg. Ranitidine. Help by decreasing acid secretion.
  • Proton pump blockers--eg. Omeprazole. Very effective in reducing irritation of the esophagus.

Surgery--

Undertaken only in cases totally refractory to drugs & also in complicated GERD.

 

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